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Pre-made Urtoxazumab benchmark antibody (Whole mAb, anti-E.coli Shiga-like toxin 2 B subunit therapeutic antibody) for drug discovery and mechanism of action (MOA) research
Cat:GMP-Bios-INN-1040
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Product Details
Anti-E.coli Shiga-like toxin 2 B subunit therapeutic antibody (Pre-made Urtoxazumab biosimilar, Whole mAb) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Urtoxazumab is a humanized monoclonal antibody against diarrhoea caused by Escherichia coli, serotype O121. The drug is designed to bind to a toxin of this bacterium, so that it can be more easily broken down and eliminated from the body.[1][2]
| Products Name (INN Index) | Pre-Made Urtoxazumab Biosimilar, Whole Mab: Anti-E.Coli Shiga-Like Toxin 2 B Subunit therapeutic antibody |
|---|---|
| INN Name | urtoxazumab |
| Target | E.coli Shiga-like toxin 2 B subunit |
| Format | Whole mAb |
| Derivation | Humanized |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 – kappa |
| VD LC | IgG1 – kappa |
| Highest_Clin_Trial (Jan '20) | NA |
| Est. Status | NA |
| 100% SI Structure | NA |
| 99% SI Structure | NA |
| 95-98% SI Structure | NA |
| Year Proposed | NA |
| Year Recommended | NA |
| Companies | Teijin?Ltd. (Tokyo Japan) |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | E.coli Shiga-like toxin 2 B subunit |
| Package |
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