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Pre-Made Torapsel Biosimilar, Fusion Protein targeting SELP fused with human IGHG1 Fc (Fragment constant): Recombinant therapeutic protein targeting CD62/CD62P/GMP140/GRMP/LECAM3/PADGEM/PSEL for drug discovery and mechanism of action (MOA) research
Cat:GMP-Bios-INN-1027
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Product Details
Pre-Made Torapsel Biosimilar, Fusion Protein targeting SELP fused with human IGHG1 Fc (Fragment constant): Recombinant therapeutic protein targeting CD62/CD62P/GMP140/GRMP/LECAM3/PADGEM/PSEL is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Torapsel is a 42-89-glycoprotein (human clone PMT21:PL85 P-selectin glycoprotein ligand 1) fused with immunoglobulin (human constant region). It has been used for the prevention of Ischemia Reperfusion Injury
| Products Name (INN Index) | Pre-Made Torapsel Biosimilar, Fusion Protein targeting SELP fused with human IGHG1 Fc (Fragment constant): Recombinant therapeutic protein targeting CD62/CD62P/GMP140/GRMP/LECAM3/PADGEM/PSEL |
|---|---|
| INN Name | torapsel |
| Target | SELP |
| Format | Fusion Protein |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | Fusion – [SELPLG (selectin P ligand, selectin P glycoprotein ligand, PSGL-1, CD162) 42-89]2 – IGHG1 Fc (Fragment constant) |
| VD LC | Fusion – [SELPLG (selectin P ligand, selectin P glycoprotein ligand, PSGL-1, CD162) 42-89]2 – IGHG1 Fc (Fragment constant) |
| Highest_Clin_Trial (Jan '20) | NA |
| Est. Status | NA |
| 100% SI Structure | NA |
| 99% SI Structure | NA |
| 95-98% SI Structure | NA |
| Year Proposed | NA |
| Year Recommended | NA |
| Companies | Wyeth Pharmaceuticals (Madison NJ USA) |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | SELP |
| Package |
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