Pre-made Technetium (99Mtc) Nofetumomab Merpentan benchmark antibody (Radiolabelled antibody, anti-MS4A1/CD20 therapeutic antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-INN-1012

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SKU GMP-Bios-INN-1012 Category Tag

Product Details

Anti-MS4A1/CD20 therapeutic antibody (Pre-made Technetium (99Mtc)
Nofetumomab Merpentan biosimilar, Radiolabelled antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Technetium (99mTc) nofetumomab merpentan (trade name Verluma) is a mouse monoclonal antibody derivative used in the diagnosis of lung cancer,[1] gastrointestinal, breast, ovary, pancreas, kidney, cervix, and bladder carcinoma.[2] The antibody part, nofetumomab, is attached to the chelator merpentan, which links it to the radioisotope technetium-99m (99mTc).[3]

Products Name (INN Index)

Pre-Made Technetium (99Mtc) Nofetumomab Merpentan Biosimilar, Radiolabelled Antibody: Anti-MS4A1/CD20 therapeutic antibody

INN Name

technetium (99mTc) nofetumomab merpentan

Target

MS4A1

Format

Radiolabelled antibody

Derivation

Mus musculus

Species Reactivity

Human

CH1 Isotype

Fab – G2b – kappa

VD LC

Fab – G2b – kappa

Highest_Clin_Trial (Jan '20)

NA

Est. Status

NA

100% SI Structure

NA

99% SI Structure

NA

95-98% SI Structure

NA

Year Proposed

NA

Companies

NeoRx?Corp. (Seattle WA USA) / Boehringer Ingelheim Pharmaceuticals (Ridgefield CT USA) / DuPont?Merck Pharmaceutical (Billerica MA USA)

Conditions Approved

NA

Conditions Active

NA

Conditions Discontinued

NA

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

MS4A1

Package

, ,

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