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Pre-made Gresonitamab benchmark antibody ( Whole mAb, anti-CLDN18;CD3E therapeutic antibody, Anti-SFTA5/SFTPJ;T3E/TCRE/IMD18 Antibody) for drug discovery and mechanism of action (MOA) research
Cat:GMP-Bios-ab-670
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Product Details
Pre-Made Gresonitamab biosimilar, Whole mAb, Anti-CLDN18;CD3E Antibody: Anti-SFTA5/SFTPJ;T3E/TCRE/IMD18 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Products Name (INN Index) | Pre-Made Gresonitamab biosimilar, Whole mAb, Anti-CLDN18;CD3E Antibody: Anti-SFTA5/SFTPJ;T3E/TCRE/IMD18 therapeutic antibody |
|---|---|
| INN Name | Gresonitamab |
| Target | CLDN18,CD3E |
| Format | Bispecific scFv-scFv-scFc |
| Derivation | Humanized |
| Species Reactivity | Human |
| CH1 Isotype | G1;G1 |
| VD LC | Kappa,Lambda |
| Highest_Clin_Trial (Jan '20) | Phase-I |
| Est. Status | Active |
| 100% SI Structure | None;None |
| 99% SI Structure | None;None |
| 95-98% SI Structure | None;None |
| Year Proposed | 2021 |
| Year Recommended | NA |
| Companies | Amgen |
| Conditions Approved | NA |
| Conditions Active | GE Junction Cancer |
| Conditions Discontinued | NA |
| Development Tech | BiTE Technology |
| Previous Name | NA |
| Gm Offical Target Name | CLDN18,CD3E |
| Package |
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