Pre-made Tadocizumab benchmark antibody ( Fab, anti-ITGA2B;ITGB3 therapeutic antibody, Anti-BDPLT16/BDPLT2/CD41/CD41B/GP2B/GPIIb/GT/GT1/GTA/HPA3/PPP1R93;BDPLT16/BDPLT2/BDPLT24/CD61/GP3A/GPIIIa/GT/GT2 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-542

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SKU GMP-Bios-ab-542 Category Tag

Product Details

Pre-made Tadocizumab benchmark antibody (Fab, anti-ITGA2B;ITGB3 therapeutic antibody, Anti-BDPLT16/BDPLT2/CD41/CD41B/GP2B/GPIIb/GT/GT1/GTA/HPA3/PPP1R93;BDPLT16/BDPLT2/BDPLT24/CD61/GP3A/GPIIIa/GT/GT2 Antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Tadocizumab is a humanized monoclonal antibody that acts on the cardiovascular system. It binds to integrin ¦ÁIIb¦Â3, a fibrinogen and fibronectin receptor found on platelets.

Products Name (INN Index)

Pre-Made Tadocizumab biosimilar, Fab, Anti-ITGA2B;ITGB3 Antibody: Anti-BDPLT16/BDPLT2/CD41/CD41B/GP2B/GPIIb/GT/GT1/GTA/HPA3/PPP1R93;BDPLT16/BDPLT2/BDPLT24/CD61/GP3A/GPIIIa/GT/GT2 therapeutic antibody

INN Name

Tadocizumab

Target

ITGA2B_ITGB3

Format

Fab

Derivation

Humanized

Species Reactivity

Human

CH1 Isotype

IgG1

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Phase-II

Est. Status

Discontinued

100% SI Structure

None

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2005

Companies

PDL BioPharma,Yamanouchi

Conditions Approved

NA

Conditions Active

NA

Conditions Discontinued

Coronary artery restenosis,Stroke,Thrombosis

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

ITGA2B_ITGB3

Package

, ,

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