Pre-made Ozoralizumab benchmark antibody ( Bispecific Single Domains (VH-VH'-VH), anti-TNFA/TNF;ALB therapeutic antibody, Anti-DIF/TNF-alpha/TNFSF2/TNLG1F;FDAHT/HSA/PRO0883/PRO0903/PRO1341 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-419
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Product Details

Pre-Made Ozoralizumab biosimilar, Bispecific Single Domains (VH-VH’-VH), Anti-TNFA/TNF;ALB Antibody: Anti-DIF/TNF-alpha/TNFSF2/TNLG1F;FDAHT/HSA/PRO0883/PRO0903/PRO1341 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Ozoralizumab is a humanized monoclonal antibody designed for the treatment of inflammatory diseases.

Products Name (INN Index)

Pre-Made Ozoralizumab biosimilar, Bispecific Single Domains (VH-VH'-VH), Anti-TNFA/TNF;ALB Antibody: Anti-DIF/TNF-alpha/TNFSF2/TNLG1F;FDAHT/HSA/PRO0883/PRO0903/PRO1341 therapeutic antibody
INN Name

Ozoralizumab
Target

TNFA,ALB
Format

Bispecific Single Domains (VH-VH'-VH)
Derivation

Bispecific antibody
Species Reactivity

Human
CH1 Isotype

NA
VD LC

NA
Highest_Clin_Trial (Jan '20)

Preregistration
Est. Status

Active
100% SI Structure

None;None
99% SI Structure

None;None
95-98% SI Structure

5m2j:D;None
Year Proposed

2011
Year Recommended

2012
Companies

Ablynx,Eddingpharm,Pfizer,Taisho Pharmaceutical
Conditions Approved

NA
Conditions Active

Rheumatoid arthritis
Conditions Discontinued

Ankylosing spondylitis,Crohn's disease,Psoriatic arthritis
Development Tech

Nanobody Technology
Previous Name

NA
Gm Offical Target Name

TNFA,ALB
Package

, ,

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