Pre-made Isecarosmab benchmark antibody ( Bispecific Single Domains (VH-VH'), anti-ADAMTSL5;ALB therapeutic antibody, Anti-THSD6;FDAHT/HSA/PRO0883/PRO0903/PRO1341 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-281

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SKU GMP-Bios-ab-281 Category Tags ,

Product Details

Pre-Made Isecarosmab biosimilar, Bispecific Single Domains (VH-VH’), Anti-ADAMTSL5;ALB Antibody: Anti-THSD6;FDAHT/HSA/PRO0883/PRO0903/PRO1341 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Products Name (INN Index)

Pre-Made Isecarosmab biosimilar, Bispecific Single Domains (VH-VH'), Anti-ADAMTSL5;ALB Antibody: Anti-THSD6;FDAHT/HSA/PRO0883/PRO0903/PRO1341 therapeutic antibody

INN Name

Isecarosmab

Target

ADAMTSL5,ALB

Format

Bispecific Single Domains (VH-VH')

Derivation

Bispecific antibody

Species Reactivity

Human

CH1 Isotype

na;na

VD LC

na,na

Highest_Clin_Trial (Jan '20)

Phase-I

Est. Status

Active

100% SI Structure

None;None

99% SI Structure

None;None

95-98% SI Structure

None;None

Year Proposed

2019

Companies

Merck

Conditions Approved

NA

Conditions Active

Solid tumours

Conditions Discontinued

NA

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

ADAMTSL5,ALB

Package

, ,

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