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Pre-made Idarucizumab benchmark antibody ( Fab, anti-Dabigatran therapeutic antibody) for drug discovery and mechanism of action (MOA) research
Cat:GMP-Bios-ab-261
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Product Details
Pre-Made Idarucizumab biosimilar, Fab: Anti-Dabigatran therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Idarucizumab, sold under the brand name Praxbind, is a monoclonal antibody used as a reversal agent for dabigatran.
| Products Name (INN Index) | Pre-Made Idarucizumab biosimilar, Fab: Anti-Dabigatran therapeutic antibody |
|---|---|
| INN Name | Idarucizumab |
| Target | Dabigatran |
| Format | Fab |
| Derivation | Humanized |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Approved |
| Est. Status | NFD |
| 100% SI Structure | 4jn2:HL:BA/4jn1:HL |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2013 |
| Year Recommended | 2014 |
| Companies | Boehringer Ingelheim |
| Conditions Approved | Blood coagulation disorders |
| Conditions Active | NA |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | Dabigatran |
| Package |
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