Pre-made Galcanezumab benchmark antibody ( Whole mAb, anti-CALCA;CALCB therapeutic antibody, Anti-CT/KC/PCT/CGRP/CALC1/CGRP1/CGRP-I/CGRP-alpha;CALC2/CGRP-II/CGRP2 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-228
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SKU GMP-Bios-ab-228 Category Tag

Product Details

Pre-Made Galcanezumab biosimilar, Whole mAb, Anti-CALCA;CALCB Antibody: Anti-CT/KC/PCT/CGRP/CALC1/CGRP1/CGRP-I/CGRP-alpha;CALC2/CGRP-II/CGRP2 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Galcanezumab, sold under the brand name Emgality, is a humanized monoclonal antibody used for the prevention of migraine. It is also used for cluster headaches.

Products Name (INN Index)

Pre-Made Galcanezumab biosimilar, Whole mAb, Anti-CALCA;CALCB Antibody: Anti-CT/KC/PCT/CGRP/CALC1/CGRP1/CGRP-I/CGRP-alpha;CALC2/CGRP-II/CGRP2 therapeutic antibody

INN Name

Galcanezumab

Target

CALCA&CALCB

Format

Whole mAb

Derivation

Humanized

Species Reactivity

Human

CH1 Isotype

IgG4

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Approved

Est. Status

NFD

100% SI Structure

None

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2015

Companies

Eli Lilly

Conditions Approved

Migraine,Cluster headache

Conditions Active

NA

Conditions Discontinued

Musculoskeletal pain

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

CALCA&CALCB

Package

, ,

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