Pre-made Etesevimab benchmark antibody ( Whole mAb, anti-SARS-CoV-2 Spike RBD therapeutic antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-196

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SKU GMP-Bios-ab-196 Category Tag

Product Details

Pre-Made Etesevimab biosimilar, Whole Mab: Anti-SARS-CoV-2 Spike RBD therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Bamlanivimab/etesevimab is a combination of two monoclonal antibodies, bamlanivimab and etesevimab, administered together via intravenous infusion as a treatment for COVID-19. Both types of antibody target the surface spike protein of SARS-CoV-2.

Products Name (INN Index)

Pre-Made Etesevimab biosimilar, Whole Mab: Anti-SARS-CoV-2 Spike RBD therapeutic antibody

INN Name

Etesevimab

Target

SARS-CoV-2 Spike RBD

Format

Whole mAb

Derivation

NA

Species Reactivity

Human

CH1 Isotype

IgG1

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Approved

Est. Status

NFD

100% SI Structure

7c01:CD

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2020

Companies

Eli Lilly and Company,Institute of Microbiology of the Chinese Academy of Sciences,Shanghai Junshi Biosciences

Conditions Approved

COVID-19

Conditions Active

NA

Conditions Discontinued

NA

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

SARS-CoV-2 Spike RBD

Package

, ,

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