Pre-made Encelimab benchmark antibody ( Whole mAb, anti-LAG3 therapeutic antibody, Anti-CD223 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-181

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SKU GMP-Bios-ab-181 Category Tag

Product Details

Pre-Made Encelimab biosimilar, Whole mAb, Anti-LAG3 Antibody: Anti-CD223 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Encelimab (formerly TSR 033) is an anti-lymphocyte activation gene-3 (LAG-3) (CD223) antibody, being developed by AnaptysBio and GlaxoSmithKline

Products Name (INN Index)

Pre-Made Encelimab biosimilar, Whole mAb, Anti-LAG3 Antibody: Anti-CD223 therapeutic antibody

INN Name

Encelimab

Target

LAG3

Format

Whole mAb

Derivation

NA

Species Reactivity

Human

CH1 Isotype

IgG4

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Phase-I

Est. Status

Active

100% SI Structure

None

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2019

Companies

Anaptys Bio,TESARO

Conditions Approved

NA

Conditions Active

Solid tumours

Conditions Discontinued

NA

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

LAG3

Package

, ,

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