Pre-made Elotuzumab benchmark antibody ( Whole mAb, anti-SLAMF7/CS1 therapeutic antibody, Anti-19A/CD319/CRACC Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-172

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SKU GMP-Bios-ab-172 Category Tag

Product Details

Pre-Made Elotuzumab biosimilar, Whole mAb, Anti-SLAMF7/CS1 Antibody: Anti-19A/CD319/CRACC therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Elotuzumab, sold under the brand name Empliciti, is a humanized IgG1 monoclonal antibody medication used in combination with lenalidomide and dexamethasone, for adults that have received 1 to 3 prior therapies for the treatment of multiple myeloma. It is also indicated for adult patients in combination with pomalidomide and dexamethasone, who have received 2 prior therapies including lenalidomide and a protease inhibitor. Administration of elotuzumab is done intravenously. Each intravenous injection of elotuzumab should be premedicated with dexamethasone, diphenhydramine, ranitidine and acetaminophen. It is being developed by Bristol Myers Squibb and AbbVie.

Products Name (INN Index)

Pre-Made Elotuzumab biosimilar, Whole mAb, Anti-SLAMF7/CS1 Antibody: Anti-19A/CD319/CRACC therapeutic antibody

INN Name

Elotuzumab

Target

SLAMF7

Format

Whole mAb

Derivation

Humanized

Species Reactivity

Human

CH1 Isotype

IgG1

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Approved

Est. Status

NFD

100% SI Structure

None

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2008

Companies

AbbVie,Australasian Leukaemia & Lymphoma Group,Bristol-Myers Squibb,PDL BioPharma

Conditions Approved

Multiple myeloma

Conditions Active

NA

Conditions Discontinued

NA

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

SLAMF7

Package

, ,

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