Pre-made Batoclimab benchmark antibody ( Whole mAb, anti-FCGRT therapeutic antibody, Anti-FCRN/FcgammaRn/alpha-chain Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-050

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SKU GMP-Bios-ab-050 Category Tag

Product Details

Pre-Made Batoclimab biosimilar, Whole mAb, Anti-FCGRT Antibody: Anti-FCRN/FcgammaRn/alpha-chain therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Batoclimab (HBM9161) is a fully human monoclonal antibody targeting the neonatal Fc receptor (FcRn) that accelerates the degradation of autoantibodies that drive NMOSD as well as other autoimmune disorders. … NMOSD is a serious autoimmune disease of the central nervous system with no approved effective treatment.

Products Name (INN Index)

Pre-Made Batoclimab biosimilar, Whole mAb, Anti-FCGRT Antibody: Anti-FCRN/FcgammaRn/alpha-chain therapeutic antibody

INN Name

Batoclimab

Target

FCGRT

Format

Whole mAb

Derivation

NA

Species Reactivity

Human

CH1 Isotype

IgG1

VD LC

Lambda

Highest_Clin_Trial (Jan '20)

Phase-III

Est. Status

Active

100% SI Structure

None

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2019

Companies

Immunovant Sciences

Conditions Approved

NA

Conditions Active

Graves¡¯ Ophtalmopathy,Myasthenia gravis,Autoimmune disorders,Neuromyelitis optica,Idiopathic thrombocytopenic purpura

Conditions Discontinued

NA

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

FCGRT

Package

, ,

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