Adeno Associated Virus (AAV) GFAP Expression Vector (AAV GFAP expression plasmid) | Reporters Optional: GFP, zsgreen, RFP, mcherry or luciferase

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AAV GFAP Expression Vector - Introduction

GeneMedi’s AAV GFAP expression vector is inserted with a human U6 (hU6) promoter to drive shRNA expression for RNA interference (RNAi) – mediated gene knockdown (KD). You can contact Genemedi for your unique reporter including GFP, zsgreen, RFP, mcherry, or luciferase.

The GFAP promoter is a astrocyte-specific protomer driven expression in vivo ( brain and CNS) and in vitro. The GFAP protomer can also drive gene expression in hepatic stellate cell.

You can produce AAV paticle in 293T cell line in high titer using GeneMedi’s AAV expression vector (overexpression, shRNA or Crispr-cas9-gRNA) with GeneMedi’s serotypes-specific AAV Rep-Cap plasmids and AAV helper plasmid.